Job title: Q9UI33
Job code: PfeHUBWd - Submitted by Anonymous on 2021-02-27 12:54:34
Sequence name:
SP|Q9UI33|SCNBA_HUMAN SODIUM CHANNEL PROTEIN TYPE 11 SUBUNIT ALPHA OS=HOMO SAPIENS OX=9606 GN=SCN11A PE=1 SV=2
Submitted sequence:
MDDRCYPVIFPDERNFRPFTSDSLAAIEKRIAIQKEKKKSKDQTGEVPQPRPQLDLKASR
KLPKLYGDIPRELIGKPLEDLDPFYRNHKTFMVLNRKRTIYRFSAKHALFIFGPFNSIRS
LAIRVSVHSLFSMFIIGTVIINCVFMATGPAKNSNSNNTDIAECVFTGIYIFEALIKILA
RGFILDEFSFLRDPWNWLDSIVIGIAIVSYIPGITIKLLPLRTFRVFRALKAISVVSRLK
VIVGALLRSVKKLVNVIILTFFCLSIFALVGQQLFMGSLNLKCISRDCKNISNPEAYDHC
FEKKENSPEFKMCGIWMGNSACSIQYECKHTKINPDYNYTNFDNFGWSFLAMFRLMTQDS
WEKLYQQTLRTTGLYSVFFFIVVIFLGSFYLINLTLAVVTMAYEEQNKNVAAEIEAKEKM
FQEAQQLLKEEKEALVAMGIDRSSLTSLETSYFTPKKRKLFGNKKRKSFFLRESGKDQPP
GSDSDEDCQKKPQLLEQTKRLSQNLSLDHFDEHGDPLQRQRALSAVSILTITMKEQEKSQ
EPCLPCGENLASKYLVWNCCPQWLCVKKVLRTVMTDPFTELAITICIIINTVFLAMEHHK
MEASFEKMLNIGNLVFTSIFIAEMCLKIIALDPYHYFRRGWNIFDSIVALLSFADVMNCV
LQKRSWPFLRSFRVLRVFKLAKSWPTLNTLIKIIGNSVGALGSLTVVLVIVIFIFSVVGM
QLFGRSFNSQKSPKLCNPTGPTVSCLRHWHMGDFWHSFLVVFRILCGEWIENMWECMQEA
NASSSLCVIVFILITVIGKLVVLNLFIALLLNSFSNEERNGNLEGEARKTKVQLALDRFR
RAFCFVRHTLEHFCHKWCRKQNLPQQKEVAGGCAAQSKDIIPLVMEMKRGSETQEELGIL
TSVPKTLGVRHDWTWLAPLAEEEDDVEFSGEDNAQRITQPEPEQQAYELHQENKKPTSQR
VQSVEIDMFSEDEPHLTIQDPRKKSDVTSILSECSTIDLQDGFGWLPEMVPKKQPERCLP
KGFGCCFPCCSVDKRKPPWVIWWNLRKTCYQIVKHSWFESFIIFVILLSSGALIFEDVHL
ENQPKIQELLNCTDIIFTHIFILEMVLKWVAFGFGKYFTSAWCCLDFIIVIVSVTTLINL
MELKSFRTLRALRPLRALSQFEGMKVVVNALIGAIPAILNVLLVCLIFWLVFCILGVYFF
SGKFGKCINGTDSVINYTIITNKSQCESGNFSWINQKVNFDNVGNAYLALLQVATFKGWM
DIIYAAVDSTEKEQQPEFESNSLGYIYFVVFIIFGSFFTLNLFIGVIIDNFNQQQKKLGG
QDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKCQGLVFDIVTSQIFDIIIISLIILNM
ISMMAESYNQPKAMKSILDHLNWVFVVIFTLECLIKIFALRQYYFTNGWNLFDCVVVLLS
IVSTMISTLENQEHIPFPPTLFRIVRLARIGRILRLVRAARGIRTLLFALMMSLPSLFNI
GLLLFLIMFIYAILGMNWFSKVNPESGIDDIFNFKTFASSMLCLFQISTSAGWDSLLSPM
LRSKESCNSSSENCHLPGIATSYFVSYIIISFLIVVNMYIAVILENFNTATEESEDPLGE
DDFDIFYEVWEKFDPEATQFIKYSALSDFADALPEPLRVAKPNKYQFLVMDLPMVSEDRL
HCMDILFAFTARVLGGSDGLDSMKAMMEEKFMEANPLKKLYEPIVTTTKRKEEERGAAII
QKAFRKYMMKVTKGDQGDQNDLENGPHSPLQTLCNGDLSSFGVAKGKVHCD
KLPKLYGDIPRELIGKPLEDLDPFYRNHKTFMVLNRKRTIYRFSAKHALFIFGPFNSIRS
LAIRVSVHSLFSMFIIGTVIINCVFMATGPAKNSNSNNTDIAECVFTGIYIFEALIKILA
RGFILDEFSFLRDPWNWLDSIVIGIAIVSYIPGITIKLLPLRTFRVFRALKAISVVSRLK
VIVGALLRSVKKLVNVIILTFFCLSIFALVGQQLFMGSLNLKCISRDCKNISNPEAYDHC
FEKKENSPEFKMCGIWMGNSACSIQYECKHTKINPDYNYTNFDNFGWSFLAMFRLMTQDS
WEKLYQQTLRTTGLYSVFFFIVVIFLGSFYLINLTLAVVTMAYEEQNKNVAAEIEAKEKM
FQEAQQLLKEEKEALVAMGIDRSSLTSLETSYFTPKKRKLFGNKKRKSFFLRESGKDQPP
GSDSDEDCQKKPQLLEQTKRLSQNLSLDHFDEHGDPLQRQRALSAVSILTITMKEQEKSQ
EPCLPCGENLASKYLVWNCCPQWLCVKKVLRTVMTDPFTELAITICIIINTVFLAMEHHK
MEASFEKMLNIGNLVFTSIFIAEMCLKIIALDPYHYFRRGWNIFDSIVALLSFADVMNCV
LQKRSWPFLRSFRVLRVFKLAKSWPTLNTLIKIIGNSVGALGSLTVVLVIVIFIFSVVGM
QLFGRSFNSQKSPKLCNPTGPTVSCLRHWHMGDFWHSFLVVFRILCGEWIENMWECMQEA
NASSSLCVIVFILITVIGKLVVLNLFIALLLNSFSNEERNGNLEGEARKTKVQLALDRFR
RAFCFVRHTLEHFCHKWCRKQNLPQQKEVAGGCAAQSKDIIPLVMEMKRGSETQEELGIL
TSVPKTLGVRHDWTWLAPLAEEEDDVEFSGEDNAQRITQPEPEQQAYELHQENKKPTSQR
VQSVEIDMFSEDEPHLTIQDPRKKSDVTSILSECSTIDLQDGFGWLPEMVPKKQPERCLP
KGFGCCFPCCSVDKRKPPWVIWWNLRKTCYQIVKHSWFESFIIFVILLSSGALIFEDVHL
ENQPKIQELLNCTDIIFTHIFILEMVLKWVAFGFGKYFTSAWCCLDFIIVIVSVTTLINL
MELKSFRTLRALRPLRALSQFEGMKVVVNALIGAIPAILNVLLVCLIFWLVFCILGVYFF
SGKFGKCINGTDSVINYTIITNKSQCESGNFSWINQKVNFDNVGNAYLALLQVATFKGWM
DIIYAAVDSTEKEQQPEFESNSLGYIYFVVFIIFGSFFTLNLFIGVIIDNFNQQQKKLGG
QDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKCQGLVFDIVTSQIFDIIIISLIILNM
ISMMAESYNQPKAMKSILDHLNWVFVVIFTLECLIKIFALRQYYFTNGWNLFDCVVVLLS
IVSTMISTLENQEHIPFPPTLFRIVRLARIGRILRLVRAARGIRTLLFALMMSLPSLFNI
GLLLFLIMFIYAILGMNWFSKVNPESGIDDIFNFKTFASSMLCLFQISTSAGWDSLLSPM
LRSKESCNSSSENCHLPGIATSYFVSYIIISFLIVVNMYIAVILENFNTATEESEDPLGE
DDFDIFYEVWEKFDPEATQFIKYSALSDFADALPEPLRVAKPNKYQFLVMDLPMVSEDRL
HCMDILFAFTARVLGGSDGLDSMKAMMEEKFMEANPLKKLYEPIVTTTKRKEEERGAAII
QKAFRKYMMKVTKGDQGDQNDLENGPHSPLQTLCNGDLSSFGVAKGKVHCD
Prediction status: completed
Prediction summary:
Cell Membrane, 26 Transmembrane helices
Detailed prediction results
Predicted membrane localization (MemLoci): Cell Membrane
Cell membrane score: 96%
Internal membrane score: -38%
Organellar membrane score: -86%
Predicted sequence features:
| Prediction | Presence | Start | End | Detail |
|---|---|---|---|---|
| Signal peptide (SPEP): | NO | - | - | not present |
| Cytoplasmic region (ENSEMBLE): | - | 1 | 120 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 121 | 146 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 147 | 166 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 167 | 181 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 182 | 198 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 199 | 215 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 216 | 224 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 225 | 248 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 249 | 252 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 253 | 278 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 279 | 343 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 344 | 358 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 359 | 370 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 371 | 400 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 401 | 579 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 580 | 596 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 597 | 606 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 607 | 630 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 631 | 645 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 646 | 676 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 677 | 688 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 689 | 721 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 722 | 752 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 753 | 767 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 768 | 783 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 784 | 811 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 812 | 1053 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1054 | 1071 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 1072 | 1091 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1092 | 1113 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 1114 | 1122 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1123 | 1147 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 1148 | 1165 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1166 | 1199 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 1200 | 1242 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1243 | 1258 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 1259 | 1281 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1282 | 1309 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 1310 | 1364 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1365 | 1385 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 1386 | 1395 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1396 | 1421 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 1422 | 1431 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1432 | 1450 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 1451 | 1459 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1460 | 1477 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 1478 | 1481 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1482 | 1518 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 1519 | 1536 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1537 | 1552 | view on sequence |
| Non cytoplasmic region (ENSEMBLE): | - | 1553 | 1578 | view on sequence |
| Transmembrane region (ENSEMBLE): | YES | 1579 | 1604 | view on sequence |
| Cytoplasmic region (ENSEMBLE): | - | 1605 | 1791 | view on sequence |
| GPI anchor (PredGPI): | NO | - | - | not present |
Annotation of similar proteins in SwissProt
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